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The GLP-1 Podcast Show - Dr. Jens Juul Holst: GLP-1 in Modern Medicine | Ep. 3

the glp-1 podcast show Dec 01, 2025

In this episode of The GLP-1 Podcast Show, Dr. Jens Juul Holst, Professor of Medical Physiology at the University of Copenhagen, joins host Areesha Moiz to discuss the discovery and development of GLP-1-based therapies. The conversation explores incretin biology, appetite regulation, metabolic pathways, and the evolution of GLP-1 drugs from basic science to global clinical use. The discussion also addresses cardiovascular outcomes, inflammation, and therapeutic challenges. Listen now on all major platforms.

What you’ll learn: 

  • GLP-1 hormone discovery
  • Mechanisms of incretin action
  • Evolution of GLP-1 therapies
  • Cardiovascular outcomes evidence
  • Managing side effects

 

Meet the guest:

Dr. Jens Juul Holst is Professor of Medical Physiology at the University of Copenhagen and Senior Group Leader at the Novo Nordisk Foundation Center for Basic Metabolic Research. His research focuses on metabolic hormones, appetite regulation, and the pathophysiology of obesity and type 2 diabetes. Known for co-discovering GLP-1, his work has shaped modern metabolic therapy. 

 

Hear his insights on The GLP-1 Podcast Show with Dr. Jens Juul Holst, available now on all major platforms.